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Early Signs of Kidney Disease & How to Protect Your Kidneys (Evidence-Based)

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One of the clearest early signs includes:

  • Foamy or bubbly urine (indicating protein leakage)

  • Frequent nighttime urination

  • Very pale or very dark urine

  • Difficulty or pain while urinating

  • Reduced urine output

Any persistent urine changes should be evaluated by a healthcare provider.


4. Back Pain Below the Ribs

Kidney pain typically appears:

  • on one side of the lower back

  • below the rib cage

  • and can radiate toward the groin

This is different from muscle pain and can signal infection, stones, or early-stage kidney damage.


5. Persistent Itching (Without Rash)

When waste builds up in the blood due to decreased kidney function, it can cause uremic itching, a deep, persistent itch with no visible rash.


6. Shortness of Breath

Excess fluid can accumulate in the lungs, or low red blood cell levels can decrease oxygen delivery, causing difficulty breathing.


7. Loss of Appetite or Metallic Taste

Toxin buildup may cause:

  • nausea

  • vomiting

  • metallic or ammonia-like taste in the mouth

These are classic signs of declining kidney function.


Major Risk Factors for Kidney Disease

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